M2SR

FluGen’s M2SR vaccine utilizes a proprietary M2 deleted, single replication (M2SR) influenza virus.

The M2 gene is essential for the influenza virus to spread in the patient and the deletion of the M2 gene restricts the virus to a single replication cycle in the host.

The body recognizes M2SR as an influenza infection and activates its robust immune response, but, because the virus can only replicate once, it cannot spread to other cells and cause symptoms of a real-world infection.

It is currently in Phase 2 Clinical trial to understand the Dose and Formulation Confirmation of Quad-NIV in Older Adults.