Vaccine Info

Ambirix Hepatitis Vaccine

Ambirix Description

Ambirix contains inactivated (killed) hepatitis A virus and ‘surface antigen’ (proteins from the surface) parts of the hepatitis B virus as active substances.

Ambirix contains the same ingredients as Twinrix.

These vaccines are used to protect against the same diseases, but Twinrix is given as a three-dose schedule whereas Ambirix is given as 2 injections 6 to 12 months apart.

Protection against hepatitis B infections may not be obtained until after the second dose.


  • Ambirix should be used only when there is a relatively low risk of hepatitis B infection during the vaccination course.
  • It is recommended that Ambirix should be administered in settings where completion of the two-dose vaccination course can be assured.

Ambirix Indication

Ambirix is indicated in non-immune children and adolescents from 1 year up to and including 15 years of age for protection against hepatitis A and hepatitis B infection.

Ambirix Dosage

A dose of 1.0 ml is recommended for subjects from 1 year up to and including 15 years of age.

The standard primary course of vaccination consists of two doses, the first administered at the selected date and the second between 6 and 12 months after the first dose.

The recommended schedule should be adhered to. Once initiated, the primary course of vaccination should be completed with the same vaccine.