Vaccine Info

Nirsevimab RSV Vaccine

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Last reviewed
June 30, 2021

Nirsevimab RSV Vaccine Description

Nirsevimab is being developed in partnership with AstraZeneca, which is the first investigational extended half-life monoclonal antibody (mAb) being developed as a passive immunization for the prevention of lower respiratory tract infections (LRTI) caused by RSV. It is designed to protect all infants experiencing their first RSV season and infants with congenital heart disease or chronic lung disease entering their first and second RSV season.

Nirsevimab RSV Vaccine Indication

Nirsevimab is designed to be administered from birth to infants born during the RSV season or at the season’s start for infants entering their first RSV season.

Nirsevimab RSV Vaccine Dosage

Nirsevimab is in clinical trials to determine the proper dosage.

Nirsevimab RSV Vaccine News

June 28, 2021 - Sanofi announced Nirsevimab shows positive topline results in RSV Phase 2/3 MEDLEY trial

July 30, 2020 - Sanofi published detailed results from the Phase 2b trial for nirsevimab showing a significant reduction in medically attended lower respiratory tract infections (LRTI), mainly bronchiolitis and pneumonia, and hospitalizations caused by the respiratory syncytial virus (RSV) in healthy preterm infants.

Nirsevimab RSV Vaccine Clinical Trials

Nirsevimab has been tested in several clinical trials.