Vaccine Info

MenABCWY Meningococcal (PF-06886992) Vaccine

Authored by
Last reviewed
September 29, 2021
Fact checked by
Robert Carlson, MD

MenABCWY Meningococcal Vaccine Description

Pfizer’s pentavalent meningococcal vaccine candidate (PF-06886992) combines its two approved meningococcal vaccines, Nimenrix™ (meningococcal group A, C, W-135, and Y conjugate vaccine) and Trumenba® (meningococcal group B vaccine).

Approvals of Nimenrix™ and Trumenba® vary by country.

MenABCWY Meningococcal Vaccine Indication

MenABCWY Meningococcal vaccine candidate is indicated to prevent meningococcal disease.

Meningococcal disease is an uncommon but serious disease that can attack without warning and lead to meningitis and serious blood infections. 

The majority of invasive meningococcal disease cases worldwide can be attributed to five Neisseria meningitidis groups (A, B, C, W, and Y). 

Together, these meningococcal groups account for 96% of all invasive meningococcal disease (IMD), with group B accounting for the majority of disease in adolescents and young adults in the U.S. and Europe.

MenABCWY Meningococcal Vaccine News

June 22, 2020 - Initiation of the Phase 3 trial is based on positive results from a proof-of-concept study in 543 adolescents and young adults. Detailed results from the proof-of-concept study have been submitted for presentation at ID Week 2020.

MenABCWY Meningococcal Vaccine Clinical Trials

Pfizer's MenABCWY Meningococcal Vaccine is currently in 4 clinical trials to determine the safety, tolerability and immunogenicity among various age groups.