Vaccine Info

Daptacel Diphtheria Vaccine


Daptacel contains 15 Lf diphtheria toxoid, 5 Lf tetanus toxoid, and acellular pertussis antigens [10 µg detoxified pertussis toxin (PT), 5 µg filamentous hemagglutinin (FHA), 3 µg pertactin, and 5 µg fimbriae types 2 and 3 (FIM)] in each 0.5-mL dose. Other ingredients per 0.5-mL dose include 1.5 mg aluminum phosphate (0.33 mg of aluminum) as the adjuvant, ≤5 µg residual formaldehyde, <50 nanogram (ng) residual glutaraldehyde and 3.3 mg [0.6% volume per volume (v/v)] 2-phenoxyethanol (not as a preservative).


Daptacel is indicated for active immunization against diphtheria, tetanus, and pertussis as a five-dose series in infants and children 6 weeks through 6 years of age (prior to 7th birthday). 


Daptacel is administered as an intramuscular injection, as a 5 dose series at 2, 4 and 6 months of age (at intervals of 6-8 weeks), at 15-20 months of age and at 4-6 years of age.

The first dose may be given as early as 6 weeks of age. Four doses of Daptacel constitute a primary immunization course for pertussis.

The fifth dose is a booster for pertussis immunization. Three doses of Daptacel constitute a primary immunization course for diphtheria and tetanus.

The fourth and fifth doses are boosters for diphtheria and tetanus immunization. 

09/30/2019 - 16:31