Vaccine Info

Ad26.Mos4.HIV HIV Vaccine

Ad26.Mos4.HIV is a tetravalent vaccine candidate containing recombinant adenovirus serotype 26 (Ad26) vectors with mosaic inserts.

Ad26.Mos4.HIV is being developed as an anti-HIV vaccine.

This vaccine candidate is administered via an intramuscular (IM) injection into the left deltoid.

In the clinical trial, participants will receive Ad26.Mos4.HIV 5*10^10 virus particles (vp) as 0.5 milliliter (mL) via (IM) injection into the left deltoid on Months 0, 3, 6, and 12 and Clade C gp140 (250 [microgram] mcg) mixed with Aluminum phosphate adjuvant as 0.5 mL IM into the right deltoid on Months 6 and 12.

May 30, 2019, Janssen Vaccines & Prevention B.V. announced they have finished the recruitment of 2600 women for the phase 2b clinical trial for Ad26.Mos4.HIV.

Clinical Trial NCT03060629:  A Study to Assess the Efficacy of a Heterologous Prime/Boost Vaccine Regimen of Ad26.Mos4.HIV and Aluminum Phosphate-Adjuvanted Clade C gp140 in Preventing Human Immunodeficiency Virus (HIV) -1 Infection in Women in Sub-Saharan Africa

June 13th, 2019