Herpes Treatments 2023

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Last reviewed
August 14, 2023
Content Overview
Herpes treatments are available in 2023

Herpes Treatments August 2023

The U.S. Centers for Disease Control and Prevention (CDC) says there is no cure for herpes as of April 21, 2023. However, the use of antiviral medicines shortens herpes outbreaks. According to Technavio, there were about 15 vendors in the Herpes treatment market. According to FMI data, the size of the global herpes labialis treatment market might increase from US$ 1.13 billion in 2023 to US$ 1.79 billion by 2033. In addition, the Acyclovir product segment reported a significant market share in the retail pharmacy segment.

Genital herpes is caused by herpes simplex virus type 1 and type 2, a common sexually transmitted disease (STD) associated with substantial health losses. A study published in February 2023 estimated 0.05 lifetime quality-adjusted life years lost per incident infection, equivalent to losing 0.05 years or about 18 days of life for one person with perfect health. 

Herpes Treatments

Acyclovir is U.S. FDA-approved to decrease pain and speed the healing of sores or blisters in people with varicella, herpes zoster, and first-time or repeat outbreaks of genital herpes. Acyclovir is also sometimes used to prevent outbreaks of genital herpes in people who are infected with HSV. Acyclovir is in a class of antiviral medications called synthetic nucleoside analogues. However, Acyclovir (valacyclovir 500 mg) will not cure genital herpes and may not stop the spread of genital herpes to other people.

Zydus Cadila commercializes Acyclovir Ointment USP (US RLD Zovirax), 5%. The first onset of genital herpes is treated with this medication. Those with weakened immune systems can also use it to treat lip and skin herpes infections that are not life-threatening.

Aurobindo Pharma Ltd. offers Valtrex® Tablets with 500mg base and 1g base for adults. However, it does not cure HSV.

Cipla Ltd. offers antiviral medicines treating viral infections like herpes labialis, herpes simplex, shingles, and genital herpes infection called ACIVIR 200 DT and ACIVIR 400 DT tablets.

Herpes Treatment Candidates 2023

AiCuris's Pritelivir (AIC316) is a potent inhibitor of HSV replication that belongs to a new chemical class and acts via a novel mechanism of action. In contrast to currently used nucleoside analogues, Pritelivir does not require activation by viral enzymes and can thus protect uninfected cells. On March 1, 2023, a clinical study suggested Pritelivir was safe and well tolerated, up to 600 mg following single and up to 200 mg following multiple once-daily doses. Considering a therapeutic dose of 100 mg once daily, pritelivir demonstrated a favorable safety and tolerability and pharmacokinetic profile in healthy subjects to support further development. However, Pritelivir does not cure herpes.

Assembly Biosciences, Inc. announced the selection of development candidate ABI-5366 (5366) to progress to IND-enabling studies for its long-acting HSV-2 helicase inhibitor program. 

Laboratoire Boreaderme Inc. and Ecogene 21 announced in September 2020 that they are focused on a Phase 2 clinical study to evaluate the safety profile of BOR15001L7 to docosanol 10% for managing cold sores in patients with recurrent herpes labialis.

A study published in May 2023 found that a molecule can effectively treat the lesions accompanying shingles and suggests the molecule may also work against the viruses that cause oral and genital herpes.

Herpes Tests 2023

The WHO announced in July 2023 that a new report on the Diagnostics Landscape for Sexually Transmitted Infections highlights diagnostics available to support scale-up of screening for STIs, including herpes. The U.S. Preventive Services Task Force published in February 2023 recommendations on screening for genital herpes infection in asymptomatic adults and adolescents, including pregnant individuals. Mylab Discovery Solutions in India launched PathoDetect™ HSV Type 1& 2 Detection kit, a multiplex real-time PCR test that detects and differentiates HSV-l and HSV-2 in a single tube. And LabCorp Herpes Simplex Virus Types 1/2, DNA PCR.

UltaLabs offers confidential herpes testing in the U.S.

Herpes Vaccines

As of August 2023, the U.S. FDA has not approved a herpes vaccine candidate.