Rheumatoid Arthritis Patients Significantly Benefited from Influenza Vaccination
Flu shots significantly reduced rheumatoid arthritis patients risk of hospitalization and mortality
A recent study conducted in Taiwan found that when Rheumatoid Arthritis (RA) patients received the annual influenza vaccine, they realized significantly lower morbidity and mortality.
Additionally, elderly RA patients saw a significant benefit after getting the flu shot.
In this retrospective, nationwide study of 3,748 patients, those with RA receiving the influenza vaccine were associated with reduced risk of hospitalization for septicemia, bacteremia or viremia, and lower risk of mortality.
Chun-Ming Chen, of the Ditmanson Medical Foundation Chiayi Christian Hospital in Chiayi City, Taiwan, and colleagues used data from the Taiwan National Health Insurance Research Database, and the Cox proportional hazards regression model was used to analyze the flu shot efficacy.
Separately, a previous study published in The Journal of Rheumatology found that it takes various methods and targeted interventions to increase RA patient flu shot vaccination rates.
At each rheumatology outpatient visit, the investigators tracked missed opportunities for influenza vaccination, which were defined as a visit in which an unvaccinated patient with no contraindications remained unvaccinated.
Healthcare professionals received a multimodal intervention that included an educational session, EMR alerts, and weekly provider-specific email reminders.
A total of 228 patients with RA were enrolled in the study. Pre-intervention, the frequency of any missed opportunities for influenza immunization was 47 percent.
This rate was reduced significantly to 23 percent post-intervention.
These investigators concluded that improved uptake of influenza immunization among patients with RA is possible with the use of a multimodal approach.
And, certain patient subgroups may require more powerful interventions to achieve comparable efficacy.
Rheumatoid arthritis is the most common type of autoimmune arthritis. It is caused when the immune system is not working properly.
It is a chronic disease that causes pain, stiffness, swelling, and limitation in the motion and function of multiple joints. Though joints are the principal body parts affected by RA, inflammation can develop in other organs as well.
An estimated 1.3 million Americans have RA, and the disease typically affects women twice as often as men.
The Taiwan study was funded by the Ministry of Health and Welfare, Grant Number: MOHW107-TDU-B-212-123004, and China Medical University Hospital, Grant Number: DMR-107-192. No conflicts of interest were disclosed.