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COVID-19 Vaccination Insufficient for Nursing Home Residents

September 13, 2021 • 3:50 pm CDT
(Precision Vaccinations)

The JAMA Network published the results of a cohort study on September 13, 2021, which suggests that an outbreak of COVID-19 can occur among highly vaccinated nursing home (NH) residents.

The researchers report a (Breakthrough Case) outbreak of COVID-19 in a 77-bed NH located in Biscarrosse, France, where most residents had been 97% vaccinated in early 2021, with the Comirnaty (Pfizer-BioNTech, BNT162b2) vaccine.

Several weeks after the vaccination campaign, a resident contracted COVID-19 outside of the facility.

The study found evidence of transmission among vaccinated NH residents, but few infected individuals developed the severe disease.

Among individuals with diagnoses, 8 residents developed the severe disease, 2 were hospitalized, and 1 unvaccinated individual died.

'To our knowledge, this is the first COVID-19 outbreak due to the B.1.1.7 coronavirus variant described among individuals well vaccinated against SARS-CoV-2.'

'The occurrence of the outbreak described in our study despite vaccination may be associated with impaired immune function associated with immunosenescence and health conditions, such as malnutrition, diabetes, and cancer, that are frequent among NH residents.'

'Previous studies have found reduced antibody response in NH populations to several COVID-19 vaccines, including Comirnaty.'

'Our study’s findings suggest that SARS-CoV-2 vaccination may not be sufficient as the sole means to prevent COVID-19 breakthrough cases among NH residents and that other prevention measures should not be abandoned in these settings.'

Note: Industry conflicts of interest by the research team were disclosed.

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