2021–2022 Influenza Season

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Last reviewed
June 5, 2021

2021-2022 Influenza Vaccine Composition

Northern Hemisphere Flu Season Vaccines

The US Food and Drug Administration’s Vaccines and Related Biological Products Advisory Committee published the influenza vaccine composition recommendation for the United States for the 2021-2022 flu season in February 2021.

These vaccine recommendations were based on several factors, including global influenza virologic and epidemiologic surveillance, genetic characterization, antigenic characterization, and the candidate vaccine viruses for production. The U.S. influenza vaccines' composition includes updates to the influenza A(H1N1)pdm09 and influenza A(H3N2) components.

The World Health Organization (WHO) issued its recommendations for the Northern Hemisphere 2021–2022 influenza vaccine composition on February 26, 2021. And the European Medicines Agency issued recommendations for the influenza virus strains that vaccine manufacturers should include in vaccines to prevent seasonal influenza from autumn 2021.

2021-2022 Northern Hemisphere Flu Vaccines

U.S. Egg-Based influenza vaccines are recommended to contain the following:

  • A/Victoria/2570/2019 (H1N1)pdm09-like virus
  • A/Cambodia/e0826360/2020 (H3N2)-like virus
  • B/Washington/02/2019 (B/Victoria lineage)-like virus
  • B/Phuket/3073/2013 (B/Yamagata lineage)-like virus (for quadrivalent vaccines)

U.S. Cell- or recombinant vaccines are recommended to contain the following:

  • A/Wisconsin/588/2019 (H1N1)pdm09-like virus
  • A/Cambodia/e0826360/2020 (H3N2)-like virus
  • B/Washington/02/2019 (B/Victoria lineage)-like virus
  • B/Phuket/3073/2013-like (B/Yamagata)-like virus (for quadrivalent vaccines)

Southern Hemisphere Flu Season News

May 27, 2021 - In the temperate zone of the southern hemisphere, influenza activity remained at the inter-seasonal level, reported the PAHO. In Brazil and the Southern Cone, Influenza activity remained low. Worldwide, influenza B detections accounted for the majority of the very low numbers of detections reported.

April 1, 2021 - Minister for Health and Wellbeing Stephen Wade said immunization providers have begun to receive stock of the influenza vaccination, helping protect the South Australian community from this deadly disease.

March 3, 2021 - The Australian Technical Advisory Group on Immunisation has released advice for immunization providers in its Statement on administering seasonal influenza vaccines in 2021. Flu vaccines through the National Immunisation Program will become available in April 2021.